VB is for beginners. I suggest either C#.net or C++.net. Both have Easy GUI creators, you don't have to code the GUI's. I like C#.net because it's relatively simple and it's really powerful. It can get really hard at times.

The problem would be for you to learn a whole new syntax different from what you know in Dev C++

Edit: another problem would be (if you use C#.net) that the user would have to have .net framework 3.5 installed SP1.